This section is for men who are about to start, or already taking hormone therapy to control their prostate cancer. This section discusses LHRH agonists which are most commonly:
LHRH agonists are injectable gonadotropin releasing hormone super-agonists (GnRH agonist), also known as a luteinizing hormone releasing hormone (LHRH) agonist. They are used to suppress production of the sex hormones (testosterone), in the treatment of prostate cancer.
In biochemistry, agonists are compounds that stimulate the production of another compound. (In contrast, antagonists are compounds that suppress the production of another compound.) LHRH agonists stimulate the production of the sex hormones testosterone. However, these hormones are regulated by feedback loops. So paradoxically, after they stimulates the production of sex hormones, the hormones are then suppressed by the body's feedback mechanisms.
Prostate cancer cells are hormone-dependent, that is, they need hormone stimulation to grow. When the hormones are eliminated, the cancer cells are inhibited.
LHRH agonists can be used alone or alongside other types of treatment. Your doctor will consider a number of different factors before deciding which is the most appropriate treatment for you.
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